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The OLIN-studies

In Norrbotten well-structured clinical epidemiological research activities on asthma, allergies, chronic obstructive pulmonary disease (COPD) and obstructive sleep apné syndrom (OSAS) are ongoing. These studies are known as Obstructive Lung Disease in Norrbotten (OLIN) and as been running since 1985. The OLIN-studies, which now is in its 25th year, has so far resulted in 9 doctoral dissertations and over 100 articles in scientific journals. Data from the OLIN-studies are also included in an additional 5 theses. Research is conducted in four research lines, 1 / asthma and allergy among adults, 2 / asthma and allergies among children and adolescents, 3 / COPD and OSAS and 4 / health economics. In total, more than 50 000 individuals aged 7-90 has been involved since the start of the study and more than half of these people are included in longitudinal studies.

The methods of research mainly include longitudinal studies of representative samples of the population for the study of the incidence (new cases), remission (recovery), relapse, risk factors and “health” factors of disease. Cross-sectional studies for measuring trends of prevalence are made at reasonable intervals. Case-reference studies are also carried out for answering more specific questions. The OLIN-studies have developed a questionnaire covering both asthma and COPD which have been used in studies in several countries. In addition, as part of the OLIN-studies, methods have developed for clinical epidemiological research, and clinical examination elements are now the cornerstones of the research. National and extensive international collaborations are underway with scientists from countries such as New Zealand, Indonesia and Vietnam in the east, to the U.S. in the west. The OLIN-studies are also well represented in the framework of the European Respiratory Society's activities.

The research is organised as a network with a base in Norrbotten County Council, with premises at the County Hall and Stadsvikens medical centre in central Luleå, and a branch in Boden at Björkskatans medical centre. The clinical patient activities that are part of the research in the OLIN-studies are carried out in cooperation with the Department of Medicine, Section of Respiratory Medicine and Allergology at Sunderby Hospital, Luleå. Most of the staff has their jobs at the Norrbotten County Council. The OLIN-studies network includes researchers from several universities, currently from the University of Umeå, University of Gothenburg, the Karolinska Institute and Luleå University of Technology. A Nordic scientific council consisting of 20 professors and associate professors, most of which are from Sweden, where all universities in Sweden (except Linköping) are represented are linked to the OLIN-studies.

The management team:
Associate Professor Eva Rönmark, health-care department of the Norrbotten County Council and senior lecturer at University of Umeå University, MD - Principal investigator and also director of research
Senior-physician Anne Lindberg, Section of Respiratory Medicine and Allergology at Sunderby Hospital
Professor Bo Lundbäck Department of Medicine / Krefting Research Centre at University of Gothenburg.

Major funders are currently Vetenskapsrådet, Heart-Lung Foundation, Asthma-Allergy Association, Norrbotten County Council, University of Umeå and the four Norrland County Councils through "Visare Norr" and ALF funds.

(The OLIN-studies website is currently down but will shortly be available)

möte med personer ur Olin-studien

Cooperation meeting

with OLIN-study people Nov. 12, 2009

samarbetsmöte med OLIN-studien
Page Manager: Madeleine Ahrnens|Last update: 11/17/2009

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